I obtained mine around 850 certified ISSAP types at the time. I do work as the senior, well.. only, security person at my organization so it seems appropriate. Prior to this gig I was a full time consultant which also fit in well.
As for RoI? Financially, none. Jokes and ribbing from co-workers has been an overwhelming success.
The only concentration that has any real market value would be the ISSEP designation. Combined with CAB and you have a real shot at being a career government auditor.